FDA clears RESPeRATE

" ..The FDA now says it [RESPeRATE] can be sold over the counter as a means to help people lower their blood pressure…."

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RESPeRATE Scientific Board Members

Dr. Cohn has served as president of both the American Society of Hypertension and International Society of Hypertension.

RESPeRATE Michael Weber, M.D.Dr. Weber is the immediate past president of the American Society of Hypertension.

Dr. Black is the President Elect of the American Society of Hypertension.



Read Bios of All Board Members »

Proven To Lower Blood Pressure In 10 Clinical Studies

RESPeRATE's ability to generate a significant and sustained reduction in blood pressure was substantiated in 10 separate clinical studies published in peer-reviewed medical journals.

  • The studies compared those who used RESPeRATE for 15 minutes a day for 8 weeks to a "control" group, using a walkman with relaxing music1, a home blood pressure monitoring4,5 or both.2
  • Clinical studies design included five randomized, controlled studies1,2,5,7, one controlled study4, and four open-label studies.3,6,8,9
  • There were 507 participants, average age of 58.
  • 78% of participants were already taking blood pressure medications, a third of whom were taking 3 or more medications.
  • Average initial office blood pressure of 150/90 mmHg despite other therapies; diet, exercise and/or medications.


The results.

  • RESPeRATE users with uncontrolled blood pressure experienced a significant decrease in office blood pressure by up to 36 points systolic and 20 points diastolic (top 10% reductions) with average reduction of 14/8 mmHg points.
  • The control treatment reduction was 9/4 mmHg, significantly less than with RESPeRATE.
  • The results were similar across genders and medication status.
  • The drop in office BP was directly related to the duration of slow breathing; those who used RESPeRATE more achieved better reductions.
  • A clinically significant, sustained reduction in blood pressure typically occurred in 3 to 4 weeks.
  • Larger reductions in office blood pressure occurred in older individuals and those with higher baseline blood pressures, whether taking antihypertensive medication or not.
  • Home blood pressure measurements (for up to 6 months of use11) and 24-hours ambulatory blood pressure monitoring3,9 have verified an all-day, lasting blood pressure lowering effect.

See RESPeRATE & You »


RESPeRATE's Peer-reviewed Articles :

[1] "Treating hypertension with a device that slows and regularizes breathing: A randomised, double-blind controlled study." Schein M, Gavish B, Herz M, Rosner-Kahana D, Naveh P, Knishkowy B, Zlotnikov E, Ben-Zvi N, Melmed RN. Journal of Human Hypertension; 2001, 15:271-278.
 
[2] "Breathing-control lowers blood pressure." Grossman E, Grossman A, Schein MH, Zimlichman R, Gavish B. Journal of Human Hypertension; 2001, 15:263-269.
 
[3] "Device-guided breathing exercises reduce blood pressure - Ambulatory and home measurements." Rosenthal T, Alter A, Peleg E, Gavish B.American Journal of Hypertension; 2001, 14:74-76.
 
[4] Nonpharmacologic Treatment of Hypertension by Respiratory Exercise in the Home Setting." E Meles, C Giannattasio, M Failla, G Gentile, A Capra, G Mancia. American Journal of Hypertension; 2004, 17:370-374.
 
[5] "Graded Blood Pressure Reduction in Hypertensive Outpatients Associated with Use of a Device to Assist with Slow Breathing." W Elliott, J Izzo, Jr., WB White, D Rosing, CS Snyder, A Alter, B Gavish, HR Black. J Clin Hypertens; 2004 6(10): 553-559.
 
[6] "Non-Pharmacological Treatment of Resistant Hypertensives by Device-Guided Slow Breathing Exercises." Viskoper , R, Shapira, I, Priluck, R, Mindlin, R, Chornia, L, Laszt, A, Dicker, D, Gavish, B, Alter, A. American Journal of Hypertension; 2003; 16:484-487.
 
[7] "High Blood Pressure Reduction in Diabetics with Interactive Device-Guided Paced Breathing: Final Results of a Randomized Controlled Study." MH Schein, A Alter, S Levine, T Baevsky, A Nessing, and B Gavish. Journal of Hypertension 2007; 25 (2), S192.
 
[8] "Blood pressure change following 8-week, 15-minute daily treatment with paced breathing guided by a device: A korean multi-center study." J H Bae, J H Kim, K H Choe, S P Hong, K S Kim, C H Kim and W H Kim. Journal of Clinical Hypertension, 2006, 8 (5), A43.
 
[9] "Device-Guided Paced Breathing Reduces Blood Pressure: Ambulatory and Office Measurements." Aydin et al. European Society of Hypertension 2008. [in print]
 
[10] "Device-Guided Breathing to Lower Blood Pressure: Case Report and Clinical Overview." W Elliott, J Izzo Medscape General Medicine, 2006; 8(3).
 
[11] Meles E, Giannattasio G, Boff L et al. Italian Society of Hypetension National Meeting, Bologna Italy, September 2002.
 

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