RESPeRATE is the only non-drug therapy that has been clinically proven over and over again to lower blood pressure.

The clinical studies on RESPeRATE have been published in numerous peer-reviewed publications including The American Journal of Hypertension and the American Heart Association Hypertension Primer.

Details of the studies:

    • Clinical studies design included five randomized controlled studies (1,2,5,7), one controlled (4) and four open-label studies (3,6,8,9)graph-bpchange2
    • The studies compared those who used RESPeRATE for 15 minutes a day for 8 weeks to a control group, using a walkman with relaxing music (1) a home blood pressure monitor (4,5) or both (2)
    • There were a total of 507 participants, average age of 58
    • 78% of participants were already taking blood pressure medications, a third of whom were taking 3 or more medications
    • Average initial office blood pressure of 150/90 mmHg despite other therapies, diet, exercise and/or medications

The Blood Pressure Lowering Results Demonstrated by RESPeRATE:

    • RESPeRATE users with uncontrolled blood pressure experienced a significant decrease in office blood pressure by up to 36 points systolic and 20 points diastolic (top 10% reductions) with average reduction of 14/8 mmHg points
    • The control treatment reduction was 9/4 mmHg, significantly less than with RESPeRATE
    • The results were similar across genders and medication status.
    • The drop in office BP was directly related to the duration of slow breathing. Those who used RESPeRATE more achieved better reductions
    • A clinically significant sustained reduction in blood pressure typically occurred in 3 to 4 weeks
    • Larger reductions in office blood pressure occurred in older individuals and those with higher baseline blood pressures, whether taking antihypertensive medication or not
    • Home blood pressure measurements (for up to 6 months of use7) and 24-hours ambulatory blood pressure monitoring3,9 have verified an all-day, lasting blood pressure lowering effect

RESPeRATE’s Peer-reviewed Articles :

[1]
“Treating hypertension with a device that slows and regularizes breathing: A randomised, double-blind controlled study.”Schein M, Gavish B, Herz M, Rosner-Kahana D, Naveh P, Knishkowy B, Zlotnikov E, Ben-Zvi N, Melmed RN.
Journal of Human Hypertension; 2001, 15:271-278.

[2]
“Breathing-control lowers blood pressure.”
Grossman E, Grossman A, Schein MH, Zimlichman R, Gavish B.
Journal of Human Hypertension; 2001, 15:263-269.

[3]
“Device-guided breathing exercises reduce blood
pressure – Ambulatory and home measurements.”

Rosenthal T, Alter A, Peleg E, Gavish B.
American Journal of Hypertension; 2001, 14:74-76

[4]
Nonpharmacologic Treatment of Hypertension by Respiratory Exercise in the Home Setting.” E Meles, C Giannattasio, M Failla, G Gentile, A Capra, G Mancia.
American Journal of Hypertension; 2004, 17:370-374.

[5]
“Graded Blood Pressure Reduction in Hypertensive Outpatients Associated with Use of a Device to Assist with Slow Breathing.”
W Elliott, J Izzo, Jr., WB White, D Rosing, CS Snyder, A Alter, B Gavish, HR Black
J Clin Hypertens; 2004 6(10): 553-559.

[6]
“Non-Pharmacological Treatment of Resistant Hypertensives by Device-Guided Slow Breathing Exercises.” Viskoper , R, Shapira, I, Priluck, R, Mindlin, R, Chornia, L, Laszt, A, Dicker, D, Gavish, B, Alter, A.
American Journal of Hypertension; 2003; 16:484-487.

[7]
“Blood pressure reduction with device-guided breathing: pooled data from 7 controlled studies.” W.J. Elliott, H.R. Black, A. Alter, B. Gavish.
Journal of Hypertension; 2004, 22(2):S116.

[8]
“Respiration and Blood Pressure.” Parati G, Izzo JL Jr, Gavish B., Third Edition. JL Izzo and HR Black, Eds. Baltimore, Lippincott, Williams, and Wilkins in Hypertension Primer, 2003, Ch. A40, p117-120.